Yes. If you're using a Kwilt Shoebox Plus, KwiltGo, Kwilt2 or Kwilt3, there are four USB connectors that allow connection to multiple drives, however if you are planning on using more than one USB powered external hard drive it will have to be self-powered(power to wall outlet) or you will have to use a powered USB hub(power to wall outlet). If you are using a Kwilt Shoebox Mini, you can use a standard USB hub sold at any computing store to connect multiple USB drives and keys to your Kwilt.
The Kwilt device will index a drive and present its content to the Kwilt app for access anytime, anywhere. When several USB storage devices are connected to one Kwilt device, you will see their individual names along with the percentage of storage used for each under the "Manage Kwilt Device" option. You can access this by tapping on the Kwilt icon at the top left corner of the Kwilt app.